A covid 19 transmission within a family cluster by presymptomatic infections in china. Presymptomatic transmission of sars cov 2 singapore january 23march 16 2020. Reports suggest that children aged 10 years can efficiently transmit sars cov 2 the virus that causes coronavirus disease 2019 covid 19 12however limited data are available on sars cov 2 transmission from young children particularly in child care settings 3to better understand transmission from young children contact tracing data collected from three covid 19 outbreaks in child. These clusters occurred during january 19march 12 and involved from two to five patients each.
Investigation of covid 19 cases in singapore identified seven clusters clusters ag in which presymptomatic transmission likely occurred. The 58 year old woman index 1 fell ill with fever fatigue and headache on 24 january. Cases in early march 2020 were clustered.
Seven clusters of covid 19 cases suggesting presymptomatic transmission. There were 9 family. Covid 19 transmission within a family cluster by presymptomatic carriers in china we report a family cluster of coronavirus disease 2019 covid 19 caused by a presymptomatic case.
These findings might also serve as a practica. On 19 january a couple participated in a temple activity to celebrate the chinese spring festival. 9 family members lived in three households in zhejiang province outside wuhan.
Recently 2 epidemiological studies on covid 19 have reported that typically asymptomatic carriers transmit the virus to close contacts resulting in aggregated infection of symptomatic covid 19 2 3. In terms of larger covid 19 studies that calculated the proportion of presymptomatic versus post symptomatic spread a study examining 468 covid 19 cases in china found that 126 of transmission. Our study confirms asymptomatic and human to human transmission through close contacts in familial and hospital settings.
Ten of the cases within these clusters were attributed to presymptomatic transmission and accounted for 64 of the 157 locally acquired cases reported as of march 16. Cases of covid 19 in china and the initial us. Cste is updating the covid 19 position statement within four months of its first interim approval by the executive board on april 5 2020.
We report epidemiologic laboratory and clinical findings for 7 patients with 2019 novel coronavirus disease in a 2 family cluster. There were 9 family members including 8 laboratory confirmed with covid 19 and a 6 year old child had no evidence of infection. On 28 march the chinese journal of epidemiology published a prospective study from zhejiang province.
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